روش جدیدی برای از بین بردن علایم بیماری به صورت کامل با استفاده از داروی جدید. این دارو هر 4 هفته یک بار به صورت تزریقی به بیماران رسانده می شود و علایم التهاب روده و عفونت هایی که متعاقب آن بوجود می آید رو از بین می برند.
LOS ANGELES (KABC) -- It's embarrassing, it's painful and almost a million people suffer in silence, some too shy to even tell their doctors. Inflammation in the intestines can make people miserable. Now a new treatment is changing patients' lives.
Ulcerative colitis occurs when ulcers and inflammation form on the lining of the colon and intestine. Uncomfortable symptoms can result, with multiple trips to the restroom every day.
"It's hard to tell your friends what's wrong, and you just kind of have to withdraw from life," said Dr. William J. Sandborn, chief of gastroenterology, UC San Diego Health System.
Sandborn says patients can have surgery, but that means removing the colon and requires an ileostomy bag.
Instead, there's an experimental therapy available.
"What we think is happening with this medication is that it's promoting healing of that inflamed lining of the bowel," said Sandborn.
MDX-1100 works by blocking a protein called chemokine, clearing it from the body so inflammation can't occur. Current drugs can hinder the immune system, lead to infection and even increase the risk of cancer. MDX-1100 promotes healing.
"It seems to be really targeting the colon, so it leaves much of the rest of the body alone," said Sandborn.
But if they stop the therapy, symptoms will come back.
Patients get an infusion of the drug about every four weeks. So far, it's shown good results in a Phase One study. It's now in Phase Two of testing. One interesting fact: smoking actually protects patients from ulcerative colitis. Smokers have about half the risk of developing the disease compared to nonsmokers.